The Duke-UNC Tobacco Treatment Specialist Training Program is a unique collaboration of three leaders in tobacco treatment, education, and research: the Duke Smoking Cessation Program, the University of North Carolina Tobacco Treatment Program and the North Carolina Division of Public Health. The training program includes findings from the most current evidence-based research on pharmacotherapy, population-based issues, practical guidance on running a practice, and targeted skills in tobacco dependence counseling. Information is provided as a highly interactive, 100% virtual experience over the course of 2 weeks, with a focus on problem-based learning activities, applied practice problems, and practice counseling. The Duke-UNC TTS course satisfies the training component required for individuals who wish to earn their National Certificate in Tobacco Treatment Practice (NCTTP) through NAADAC, and participants earn up to 28.75 CME hours through Duke CME.